Testis Tumors

Malignant tumors of the testis.

Classification of tumors of testis.

In adult patients, testicular tumors consist predominantly of seminoma, embryonal carcinoma, teratoma, choriocarcinoma and mixtures of these. In infants and children, yolk sac tumor and teratoma are the usual tumors; in older age patients, it is predominantly spermatocytic seminoma and malignant lymphoma, although the others may occur as well. Leydig and Sertoli-granulosa cell tumors occur in a...

Bilateral Synchronous Testis Tumors of Different Histology: A Case Report

Background: Bilateral synchronous testis germ cell tumors with different histopathology are not common. Case Presentation: Here, a case of 27-year-old male who is reported presented with bilateral testicular swellings. There was a high α-fetoprotein level with bilateral lesions on scrotal USG. Bilateral orchiectomy was performed. According to pathology report, there was a right testicular semi...

Leydig cell tumors of the testis.

Leydig cell tumors represent approximately one to three percent of all testicular tumors. Whereas in experimental animals predisposing conditions include administration of chemical carcinogens, hormones and heavy metals, environmental or endogenous factors in man are presently unrecognized. Leydig cell tumors do not show preferential lateralization or tendency for bilaterality. The symptoms are...

Investigating specific expression of ADAM29, FTHL17, and HORMAD1 cancer/testis genes in glioblastoma tumors

Introduction: Glioblastoma primary brain tumor.Immunotherapy is a promising therapeutic adjuvant in fighting against this cancer.  Cancer/testis antigens (CTAs) are a group of tumor-associated antigens that are typically restricted to adult testis, but they are aberrantly expressed in several types of cancers, especially in advanced cancers with stem-like characteristics. These tumor-associate...